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Psychedelic Neuroscience Quiz, 24 Questions
Test your basic knowledge in neuroscience and on psychedelics
Matthew 10:16 "Be as wise as a serpent".The enemy is all about the knowledge, and using it to dumb down their opponents mentally, spiritually, and physically, and then use that scientific knowledge to enhance their own cognition and biology.
HerbsPedia Psychedelic/Neuroscience Quiz, Multiple Choice.
Original blog: https://herbspedia.org/how-psychedelics-affect-the-brain.html
Grab a notebook, and a pen. Good luck! =)
(1) Serotonergic psychedelics affect the 5-HT2A receptors, found predominantly in cortical regions of the brain.
A) True
B) False
(2) What are cortical regions of the brain?
A) The area in the back above your neck.
B) It's near the pineal gland in the center of your brain
C) It is the gray matter of the brain. Lying right under the meninges, the cerebral cortex divides into four lobes: frontal, temporal, parietal and occipital lobes, each with a multitude of functions
D) There's no such thing as cortical regions of the brain.
(3) Common Serotonergic psychedelics include things like LSD(and natural lysergics like LSA/LSH, etc), Psilocybin(4-po-DMT)[and Psilocin(4-HO-DMT).
A) False
B) True
(4) What happens when any of the frontal lobe areas are damaged?
A) Neuroplasticity is induced through t-cell upregulation
B) weakness and impaired execution of motor tasks of the contralateral side occur
C) Heightened awareness
D) Mysterious talents emerge
(5) Which is true about the inferolateral areas of the dominant hemisphere (usually left side) of the frontal lobe?
A) They have an unknown purpose
B) They are responsible for unconscious storage
C) They control movement and impulsive behavior
D) They are the expressive language area (Broca area, Brodmann areas 44 and 45), to which damage will result in a non-fluent expressive type of aphasia.
(6) According to the National Library Of Medicine, the frontal lobes areas are also associated with:
A) higher functioning processing, such as regulating emotions, social interactions, and personality.
B) increases in the connections between neuron
C) minimal mental activity, especially during wakefulness.
D) decreased global connectivity, and increased brain entropy (i.e. brain signal diversity)
(7) Psilocybin has been found by researchers to:
A) Suppress the limbic system
B) increase brain entropy (i.e. brain signal diversity)
C) Kill brain cells
D) Damage neurons
(8) A single dose of psilocybin, the active compound in "magic mushrooms", given to mice prompted a long-lasting increase in the connections between neurons.
A) True
B) False
(9) Studies show that Psilocybin induces a decreased in ______ and _____ band, but an increase in _____ and ____ frequencies.
A) decreases alpha and beta, increases delta and gamma
B) increases delta and beta, increases alpha and gamma
C) decreases gamma and beta, increases alpha and delta
D) None of the above
(10) True or False: Beta waves are high-frequency, low-amplitude brain waves that are commonly observed in an awaken state. They are involved in conscious thought and logical thinking, and tend to have a stimulating effect. Having the right amount of beta waves allows us to focus.
A) False
B) True
(11) True or false: Delta waves are the slowest recorded brain waves in human beings. Delta waves are high-amplitude brain waves and are associated with deep sleep stages. The delta waves are also associated with different brain functions other than deep sleep, e.g., high frontal delta waves in awake subjects are associated with cortical plasticity
A) True
B) False
(12) Gamma Waves refer to neural oscillations in the frequency range of approximately:
A) 10-20 Hz.
B) 210-29 Hz.
C) 30-100 Hz.
D) 101-200 Hz.
(13) Gamma brain waves:
A) Make us sleepy and unconscious
B) indicate the synchronization of different nerve cells working together in a network to carry out specific cognitive or motor functions.
C) Induces rem sleep
D) increases t-cell production
(14) Gamma waves and fast rhythms likely play a role in neural communication, reflecting information from the external world to the brain.
A) True
B) False
(15) High frontal delta waves in awake subjects are associated with cortical plasticity.
A) True
B) False
(16) What are the functions of the temporal lobes?
A) To convert sensory input into tangible perception.
B) The temporal lobes are most commonly associated with processing auditory information and with the encoding of memory
C) To serve as a processing center for processing visual input from the eyes.
D) The temporal lobe controls the flow of electrons in various parts of the brain.
(17) Bilateral lesions in the amygdala such as in Herpes simplex encephalitis may cause Kluver-Bucy syndrome. In this syndrome, patients would experience dis-inhibited behavior such as hyperphagia, hypersexuality, and hyper-orality.
A) True
B) False
(18) Areas in the parietal lobe are responsible for integrating sensory information, including touch, temperature, pressure and pain..
A) True
B) False
(19) Synesthesia is "a rare neurological condition, describes an involuntary, automatic union of the senses or secondary experience caused by an external stimulus. The word synesthesia comes from the Greek meaning "to perceive together."
A) True
B) False
(20) Recent imaging studies have found changes in functional coupling between frontal and parietal brain structures, suggesting a modification in information flow between brain regions during acute effects of psilocybin.
A) True
B) False
(21) The occipital lobe is the visual processing area of the brain. It is associated with visuospatial processing, distance and depth perception, color determination, object and face recognition, and memory formation.
A) True
B) False
(22) True or false: This is a real quote from a scholarly source: "The review clearly shows that color can carry important meaning and can have an important impact on people's affect, cognition, and behavior."
A) True
B) False
(23) Most psychedelics effect a part of the brain where a receptor cite called the 2a receptor can be found. It is located in the part of the brain where major computational units in the brain exist, where all your:
A) auditory processing centers are
B) libido functions reside
C) unconscious stuff is, where your imagination, your memories and all of that, are all input into these special cells that processes the information
D) Cells are reprogrammed according to sensory input.
(24) lysergic acid diethylamide (LSD) induces an altered state of consciousness that resembles dreaming.
A) True
B) False
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1) A
Source(s):
https://pmc.ncbi.nlm.nih.gov/articles/PMC10634557/ Cameron LP, Benetatos J, Lewis V, Bonniwell EM, Jaster AM, Moliner R, Castrén E, McCorvy JD, Palner M, Aguilar-Valles A. Beyond the 5-HT2A Receptor: Classic and Nonclassic Targets in Psychedelic Drug Action. J Neurosci. 2023 Nov 8;43(45):7472-7482. doi: 10.1523/JNEUROSCI.1384-23.2023. PMID: 37940583; PMCID: PMC10634557.
2) C
Source(s):
Javed K, Reddy V, Lui F. Neuroanatomy, Cerebral Cortex. [Updated 2023 Jul 25]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537247
3) B, True
Sources:
https://pmc.ncbi.nlm.nih.gov/articles/PMC10634557/ Cameron LP, Benetatos J, Lewis V, Bonniwell EM, Jaster AM, Moliner R, Castrén E, McCorvy JD, Palner M, Aguilar-Valles A. Beyond the 5-HT2A Receptor: Classic and Nonclassic Targets in Psychedelic Drug Action. J Neurosci. 2023 Nov 8;43(45):7472-7482. doi: 10.1523/JNEUROSCI.1384-23.2023. PMID: 37940583; PMCID: PMC10634557.
Glatfelter, Grant C., et al. "Receptor binding profiles for tryptamine psychedelics and effects of 4-propionoxy-N, N-dimethyltryptamine in mice." ACS Pharmacology & Translational Science 6.4 (2023): 567-577.
Mishrakiâ€Berkowitz, Tehila, et al. "The psilocin (4â€hydroxyâ€N, Nâ€dimethyltryptamine) and bufotenine (5â€hydroxyâ€N, Nâ€dimethyltryptamine) case: ensuring the correct isomer has been identified." Journal of Forensic Sciences 65.5 (2020): 1450-1457.
4) B
Source(s):
Javed K, Reddy V, Lui F. Neuroanatomy, Cerebral Cortex. [Updated 2023 Jul 25]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537247
5) D
Source(s):
Javed K, Reddy V, Lui F. Neuroanatomy, Cerebral Cortex. [Updated 2023 Jul 25]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537247
6) A
Source(s):
Javed K, Reddy V, Lui F. Neuroanatomy, Cerebral Cortex. [Updated 2023 Jul 25]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537247
7) B
Source(s):
Nikolic, Marek, et al. "Psilocybin alters brain activity related to sensory and cognitive processing in a time-dependent manner." medRxiv (2024): 2024-09.
8) A, True
Source(s):
https://news.yale.edu/2021/07/05/psychedelic-spurs-growth-neural-connections-lost-depression
9) A
Source(s):
Nikolic, Marek, et al. "Psilocybin alters brain activity related to sensory and cognitive processing in a time-dependent manner." medRxiv (2024): 2024-09.
10) B, True
Source(s):
https://www.sciencedirect.com/topics/medicine-and-dentistry/beta-wave
11) A, True
https://www.sciencedirect.com/topics/neuroscience/delta-wave
12) C
https://www.sciencedirect.com/topics/neuroscience/gamma-wave
13) B
https://www.sciencedirect.com/topics/neuroscience/gamma-wave
14) A, True
https://pubmed.ncbi.nlm.nih.gov/18439878/
15) A, True
https://www.sciencedirect.com/topics/neuroscience/delta-wave
16) B
https://www.health.qld.gov.au/abios/asp/btemporal_lobes
17) A, True
https://www.health.qld.gov.au/abios/asp/btemporal_lobes
18) A, True
https://qbi.uq.edu.au/brain/brain-anatomy/lobes-brain
19) A, True
https://sites.dartmouth.edu/dujs/2013/03/05/what-is-synesthesia/
20) A, True
https://pmc.ncbi.nlm.nih.gov/articles/PMC4571623/
21) A, True
https://www.ncbi.nlm.nih.gov/books/NBK544320/
22) A, True
Elliot, Andrew J., and Markus A. Maier. "Color psychology: Effects of perceiving color on psychological functioning in humans." Annual review of psychology 65.1 (2014): 95-120.
23) C
Hamiltons Pharmacopeia Season 3 Episode 6 (Hamilton is an academic researcher and journalist) [https://youtu.be/E-t84yicaOE?si=GXE4IbPticyyT8MR]
Psychedelic Researcher David E Nichols. https://en.m.wikipedia.org/wiki/David_E._Nichols
24) A, True
Kraehenmann, Rainer, et al. "Dreamlike effects of LSD on waking imagery in humans depend on serotonin 2A receptor activation." Psychopharmacology 234 (2017): 2031-2046.
Academic citations:
Cited above!
Other resources:
M.A.P.S. Ethnobotanical Studies By Scholars
PubChem - pubchem.ncbi.nlm.nih.gov