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Mescal Beans
Sophora secundiflora
Genesis 3:3 But of the fruit of the tree which is in the midst of the garden, God hath said, Ye shall not eat of it, neither shall ye touch it, lest ye die. And the serpent said unto the woman, Ye shall not surely die: For God doth know that in the day ye eat thereof, then your eyes shall be opened, and ye shall be as gods, knowing good and evil. And when the woman saw that the tree was good for food, and that it was pleasant to the eyes, and a tree to be desired to make one wise, she took of the fruit thereof, and did eat, and gave also unto her husband with her; and he did eat.
Nicknames: Frijolillo;[1] Mescal Bean;[1]
Classification: The large red seeds, commonly known as "mescal beans" produce and contain the highly poisonous alkaloid known as cytisine (or sophorine), a substance that's related to nicotine, and widely cited as a narcotic and hallucinogen[1] I believe that deliriant would be a better label than hallucinogen. Anything that's toxic, and potentially deadly, that's said to be a "hallucinogen", I label a deliriant instead. They're bad news. Don't eat the fruit. Deliriant's are known for causing delirium, rather than a lucid good time that people report from psychedelics.
It's very important to be able to discern the difference, because there seems to be a trend of people labeling deadly deliriant's as "hallucinogens". A psychedelic and a deliriant are NOT THE SAME THING. A deliriant causes delirium, which is defined as: "a clinical syndrome characterized by confusion, attentional disturbances, and cognitive impairment, often seen in elderly patients."[2] Here are some examples.. Psychedelics include: mescaline, psilocybin, DMT, Ibogaine, LSA, etc. Deliriants include: scopolamine, henbane, datura, bella donna, mandrake. Psychedelics have therapeutic applications, deliriants should never be consumed.
Plant Family: Fabaceae;[5] Genus: Dermatophyllum[5] Species: D. secundiflorum[5]
Ethnobotany: The red seeds of Sophora secundiflora (mescal beans) have been used by the Native Americans as a narcotic and "hallucinogen"[3], but really I believe that "deliriant" is more accurate. They are deadly, and even one seed may kill a person, but not always. It truly reminds me of the Garden Of Eden, and the fruit of the tree of the knowledge, of good and evil. "In the day ye eat thereof, ye shall surely DIE!" Native American tribes would utilize the mescal beans during ceremonies, in which visions were experienced by those consuming them. Reminds me of: "In the day ye eat thereof, ye shall be as GODS" Interesting no?
I read something very interesting when thumbing through the third academic source that I pulled up when looking for information on the mescal beans. It reads: "In 1878, Wiegand (5) published the only case report of human intoxication in which an adult subject experienced headache, several bowel movements, great difficulty in wa lking, and sleep which lasted several hours when one-fourth of a seed (approximately 150 mg) was consumed orally. No mention was made of any hallucinogenic effects. The only information available regarding the proposed hallucinogenic activity of mescal beans is found in ethnographic reports regarding their use by Native Americans."[3] According to this source, a test subject claims the beans produced no psychoactive effects, and the only people who have claimed to have experienced "hallucinogenic" effects from the consumption of the beans were the Native Americans... Could it be that the effects are not coming from the mecsal beans at all, but rather from a serpent spirit? FACT: The occult uses poisonous plants to practice necromancy, divination, and other things listed in Deuteronomy 18.[4] Do you see the connection? It brings them closer to death, thus nearer to the other-side. This helps them commune with spirits that pretend to be dead ancestors and whoever else. It's forbidden in the bible because it's extremely dangerous and leads to a curse.
Natural Habitat: North American, mostly near Texas.
OG Observations: If this stuff were a good time ( and it's NOT ), it would be insanely popular and you would hear about it all the time, plus the government would have stepped in and outlawed it by now. There seems to be a satanic pharmakeia trend going on where people are being told that deliriants and poisons are "medicine" and "hallucinogens". I'm here to combat it.
Phytochemicals: sophorine and cytisine(the two are the same, from different botanicals);[1] quinolizidine alkaloids, epi-lupinine and delta-dehydrolupanine were isolated.[3]
How phytochemistry, ethnobotany, pharmacognosy, and pharmacology are all related.
Phytochemistry is the study of the pharmacology of plants. Phytochemist isolate phytochemicals out of herbal medicine, and then study those isolates(as they're called) to determine their medicinal properties. It's because of what the ethnobotanist do, that they are able to know which plants to study. You could say that phytochemist study ethnobotanicals in their phytochemistry laboratory. The pharmacology of those phytochemicals is then determined. Pharmacognosy is the only field of study left that I haven't touched base on yet. It's the study of crude drugs made from natural sources. In the phytochemistry lab, the studies start off with crude extracts, and then from there, they are broken down even futher(isolated), until they can list off a list of phytochemical components that are identified in those extracts.Pharmacological / Medicinal Properties:
The plant is poisonous. It appears that micro-doses of the poisonous seeds were causing some type of narcotic high. The main component "sophorine" is similar in structure to nicotine[1], thus it makes sense that it would produce some type of high, because nicotine has effects to a certain extent. I don't doubt that it can produce a narcotic buzz in micro-doses, but the academic sources that I've pulled up on this ethnobotanical indicate that there's no hallucinogenic or psychedelic chemical components that exist in the seeds of mescal bean. The sophorine must be messing with the nicotine system somehow, creating whatever effects the seeds produce. From the test subjects experience report, it sounded like he just consumed some poison and felt lousy. While there is such a thing as using medicine as poison(Arndt–Schulze law)[6], it would only make sense to do so in a life or death situation where all you had access to was the mescal beans. The Arnd't Shulze Law states that: "For every substance, small doses stimulate, moderate doses inhibit, large doses kill."[7]Related Ethnobotanicals: Red Larkspur (Delphinium nudicaule)
Buy Sophora secundiflora Here
Academic citations:
[2] https://www.ncbi.nlm.nih.gov/books/NBK470399/ The National Library Of Medicine, Delirium
[3] HATFIELD, GM, et al. "All hn'estigalioll of Sophora st'Clllldij1uI Seeds (Mcsealhculls)."
[4] Hatsis, Thomas. The witches' ointment: The secret history of psychedelic magic. Simon and Schuster, 2015.
[6] Helmstädter, Axel. "Is there a tonic in the toxin? The Arndt–Schulze law as an explanation for non-linear dose–response relationships." Info (2008): 29.
Robbers, James E, et al. Pharmacognosy and Pharmacobiotechnology. Baltimore, Williams & Wilkins, 1996.
Encyclopedia Sources:
[5] Wikipedia contributors. (2024, December 7). Dermatophyllum secundiflorum. In Wikipedia, The Free Encyclopedia. Retrieved 04:44, December 10, 2024, from https://en.wikipedia.org/w/index.php?title=Dermatophyllum_secundiflorum&oldid=1261769921
[7] Wikipedia contributors. (2024, December 7). Arndt-Schulz_rule. In Wikipedia, The Free Encyclopedia. Retrieved 11:30, December 10, 2024, from https://en.wikipedia.org/wiki/Arndt-Schulz_rule
Other resources:
M.A.P.S. Ethnobotanical Studies By Scholars
PubChem - pubchem.ncbi.nlm.nih.gov